THZ2
Rincian produk
Tag produk
| Ukuran Pek | Kasadiaan | Harga (USD) |
| 100 mg | Aya sasayogian | 500 |
| 500 mg | Aya sasayogian | 800 |
| 1g | Aya sasayogian | 1200 |
| Langkung Ukuran | Meunang Tanda kutip | Meunang Tanda kutip |
Ngaran Kimia:
N-[3-[[5-chloro-4-(1H-indol-3-yl) pirimidin-2-yl]amino]fenil]-3-[[(E)-4-(dimethylamino)tapi-2- enoyl]amino]benzamide
Kode SMILES:
O=C(NC1=CC=CC(NC2=NC=C(Cl)C(C3=CNC4=C3C=CC=C4)=N2)=C1)C5=CC=CC(NC(/C=C/CN) (C)C)=O)=C5
Kodeu InChi:
InChI=1S/C31H28ClN7O2/c1-39(2)15-7-14-28(40)35-21-9-5-8-20(16-21)30(41)36-22-10-6- 11-23(17-22)37-31-34-19-26 (32)29(38-31)25-18-33-27-13-4-3-12-24(25)27/h3-14,16-19,33H,15H2,1-2H3,(H, 35,40)(H,36,41)(H,34,37,38)/b14-7+
Konci InChi:
FONRCZUZCHXWBD-VGOFMYFVSA-N
kecap konci:
THZ-2, THZ 2, THZ2, 1604810-84-5
Kalarutan:Leyur dina DMSO
Panyimpenan:0 - 4°C kanggo jangka pondok (poé ka minggu), atanapi -20°C kanggo jangka panjang (bulan).
Katerangan:
THZ2, analog tina THZ1, kalayan poténsial pikeun ngubaran kanker payudara Triple-négatip (TNBC), éta mangrupikeun inhibitor CDK7 anu kuat sareng selektif anu ngatasi instability THZ1 dina vivo. IC50: CDK7 = 13,9 nM; Sél TNBC = 10 nM
Sasaran: CDK
