MSC2530818
Product Detail
Product Tags
| Pack Size | Availability | Pretium (USD) |
| 100mg | In Stock | 400 |
| Plus Sizes | Get Quotes | Get Quotes |
Nomen chemicum:
[(2S)-2-(4-Chlorophenyl) pyrrolidin-1-yl]-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)methanone
SMILES Code:
O=C(N1[C@H](C2=CC=C(Cl)C=C2)CCC1)C3=CN=C(NN=C4C)C4=C3
InChi Code:
InChI=1S/C18H17ClN4O/c1-11-15-9-13(10-20-17(15)22-21-11)18(24)23-8-2-3-16(23)12-4- 6-14(19)7-5-12/h4-7,9-10,16H,2-3,8H2,1H3,(H,20,21,22)/t16-/m0/s1
InChi Key:
ODRITQGYYWHQGM-INIZCTEOSA-N
Keyword:
MSC2530818, MSC-2530818, MSC 2530818, 1883423-59-3
Solubilitas:Solutum in DMSO
Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).
Descriptio:
MSC2530818 Potens, selectiva, et oretenus Bioavailable CDK8 Inhibitor cum CDK8 IC50 = 2.6 nM; Vaticinium humanum PK: CL ~ 0.14 L/H/Kg; t1/2 ~ 2.4h; F> 75%. MSC2530818 excellentem kinasum selectivity, biochemicum et cellulosam potentiam, microsomalem stabilitatem ostendit, et viva voce bioavailable est. MSC2530818 demonstrat idoneam potentiam et selectivam progrediendi in studiis praeclinicis in vivo efficacia et salute.
Target: CDK
