Verucerfont

Nomen chemicum:

(S) -3-(4-methoxy-2-methylphenyl)-2,5-dimethyl-N-(1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl)pyrazolo[1; 5-a] pyrimidin-7-amine

SMILES Code:

CC[C@H](NC1=CC(C)=NC2=C(C3=CC=C(OC)C=C3C)C(C)=NN12)C4=NC(C)=NO4

InChi Code:

InChI=1S/C22H26N6O2/c1-7-18(22-24-15(5)27-30-2225-19-11-13(3)23-21-20(14(4)26-28( 19)21)17-9-8-16(29-6)10-12(17)2/h8-11,18,25H,7H2,1-6H3/t18-/m0/s1

InChi Key:

VKHVAUKFLBBZFJ-SFHVURJKSA-N

Keyword:

Verucerfont, GSK561679, GSK 561679, GSK-561679, NBI77860, NBI 77860, NBI-77860, 885220-61-1

Solubilitas:Solutum in DMSO

Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).

Descriptio:

"Verucerfont, etiam GSK561679 et NBI77860 notus, impugnator est CRF-1. Verucerfont impedit receptatorem CRH-1 et sic reducit ACTH remissionem sequentes accentus chronica. In inquisitione est potentia curatio ad alcoholismum, sicut accentus longus saepe est. factor in utroque evolutionis alcoholismo et relapsus in alcoholicis recuperandis. Promittens eventus ostendit in studiis animalibus, sed in hominibus non est probatum.

Target: CRF-1