Voruciclib

Voruciclib
  • Nomen:Voruciclib
  • Catalogue No.CPD100904
  • CAS No.:1000023-04-0
  • Pondus hypotheticum:469.84
  • Formulae chemica:C22H19ClF3NO5
  • Investigationes scientificae tantum, non aegros.

    Product Detail

    Product Tags

    Pack Size Availability Pretium (USD)

    Nomen chemicum:

    2-(2-Chloro-4-(trifluoromethyl)phenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl) -4-unum

    SMILES Code:

    O=C1C=C(C2=CC=C(C(F)(F)F)C=C2Cl)OC3=C([C@H]4[C@H](CO)N(C)CC4)C (O)=CC(O)=C13

    InChi Code:

    InChI=1S/C22H19ClF3NO5/c1-27-5-4-12(14(27)9-28)19-15(29)7-16(30)20-17(31)8-18(32-21( 19)20)11-3-2-10(6-13(11)23)22(24,25)26/h2-3,6-8,12,14,28-30H,4-5,9H2; 1H3/t12-,14+/m1/s1

    InChi Key:

    MRPGRAKIAJJGMM-OCCSQVGLSA-N

    Keyword:

    P1446A05, P1446A-05, P1446A 05, Voruciclib

    Solubilitas: 

    Repono: 

    Descriptio:

    Voruciclib, etiam ut P1446A-05, est interdum inhibitor kinasus specificae pro cyclino-dependens kinase 4 (CDK4) cum actu antineoplastico potentiale. CDK4 inhibitor P1446A-05 specialiter vetat CDK4 mediatum G1-S tempus transitus, cellam cyclicam capiens et incrementum cellae cancer inhibens. Serinum/threoninum kinasum CDK4 in complexu cum D-type G1 cyclinis invenitur et primum kinasus ad excitationem mitogenicam reducitur, cellulas a quiescente stadio in G1/S activitate cycli solvens; Complexiones CDK-cyclinae ostensae sunt phosphorylate retinoblastomae (Rb) transcriptionis factoris in primo G1, ac divellens histonum deacetylasium (HDAC) et reprimendum transcriptionale interclusio.

    Target: CDK4


  • Previous:
  • Next:

  • Related Products

    Whatsapp Online Chat!