| CAT # | Product Name | Descriptio |
| CPDB0099 | Quizartinib; AC-010220; AC-220 | Quizartinib inhibitor est kinasis tyrosinae FMS relatae 3 (FLT3; Kd = 1.6 nM) et selectivam altam demonstrat FLT3 cum probata contra tabulam 227 kinases additas. Inhibet propagationem leukemia cell lineae MV4-11 humanae, quae mutationem homozygoam FLT3-ITD accipit, cum IC50 valore 0.56 nM.1 In 1 mg/kg/die, quizartinib in mure superstitem extendere monstratum est. exemplar of FLT3-ITD myeloidalis leukemia acuta et tumores in musculo xenografo dependens ad 10 mg/kg tumores extirpare. |
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