T-26c

Ainm Ceimigeach:

4-(((2-(3-methoxybenzyl)carbamoyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl)methoxy)methyl)benzoic acid

Còd SMILES:

O=C(O)C1=CC=C(COCC2=CSC(N=C(C(NCC3=CC=CC(OC)=C3)=O)N4)=C2C4=O)C=C1

Còd InChi:

InChI=1S/C24H21N3O6S/c1-32-18-4-2-3-15(9-18)10-25-22(29)20-26-21(28)19-17(13-34-23( 19)27-20)12-33-11-14-5-7-16(8-6-14)24(30)31/h2-9,13H,10-12H2,1H3,(H,25,29 (H,30,31)(H,26,27,28)

iuchair InChi:

CDQRIIUMNLMHRH-UHFFAOYSA-N

Facal-luirg:

T-26c, T26c, T 26c, 869296-13-9

Solubility:Soluble ann an DMSO

Stòradh:0 - 4 ° C airson geàrr-ùine (làithean gu seachdainean), no -20 ° C airson ùine fhada (mìosan).

Tuairisgeul:

Tha T-26c na neach-dìon matrix metalloproteinases 13 (MMP-13) fìor chumhachdach, roghnach agus cealla-permeable. Tha T-26c cuideachd a’ cur bacadh air briseadh sìos collagen ann an IL-1b agus cartilage air a bhrosnachadh le oncostatin M.

Targaid: MMP-13