AZD-7594
Mion-fhiosrachadh toraidh
Bathar Tags
Meud pacaid | Ri fhaotainn | Prìs (USD) |
100mg | Anns a’ bhùth | 500 |
500mg | Anns a’ bhùth | 800 |
1g | Anns a’ bhùth | 1200 |
Barrachd mheudan | Faigh Quotes | Faigh Quotes |
Ainm Ceimigeach:
3-(5-((1R,2S)-2-(2,2-difluoropropanamido)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-il)propoxy)-1H-indazol -1-il) -N-(tetrahydrofuran-3-yl) benzamide
Còd SMILES:
O=C(NC1COCC1)C2=CC=CC(N3N=CC4=C3C=CC(O[C@H](C5=CC=C(OCCO6)C6=C5))[C@@H](NC(C( F)(F)C)=O)C)=C4)=C2
Còd InChi:
InChI=1S/C32H32F2N4O6/c1-19(36-31(40)32(2,33)34)29(20-6-9-27-28(16-20)43-13-12-42-27) 44-25-7-8-26-22(15-25)17-35-38(26)24-5-3-4-21(14-24)30(39)37-23-10-11- 41-18-23/h3-9,14-17,19,23,29H,10-13,18H2,1-2H3,(H,36,40)(H,37,39)/t19-,23? ,29-/m0/s1
iuchair InChi:
ZZWJKLGCDHYVMB-QMQODZDESA-N
Facal-luirg:
AZD-7594, AZD 7594, AZD7594, AZ13189620, AZ-13189620, AZ 13189620, 1196509-60-0
Solubility:Soluble ann an DMSO
Stòradh:0 - 4 ° C airson geàrr-ùine (làithean gu seachdainean), no -20 ° C airson ùine fhada (mìosan).
Tuairisgeul:
Tha AZD-7594, ris an canar cuideachd AZ13189620, na modulator receptor glucocorticoid roghnach (GCCR). Tha AZD-7594 ann an deuchainnean clionaigeach ìre II le AstraZeneca airson làimhseachadh asthma meadhanach gu meadhanach. Tha e cuideachd ann an deuchainnean clionaigeach ìre I airson làimhseachadh eas-òrdugh sgamhain cnap-starra (COPD).
Targaid: GCCR