CAT # | Ainm toraidh | Tuairisgeul |
CPD111306 | 7-bromo-2,4,6-trichloro-8-fluoroquinazoline | |
CPD113109 | ARS-1323-Alcaine | ARS-1323-alkyne, inneal-dìon pòcaid switch-II (S-IIP). |
CPDP801183 | VVD-214;RO7589831;VVD-133214 | Tha VVD-214 na neach-dìon allosteric marbhtach helicase WRN. |
CPDP801366 | Inlexisertib;DCC-3116 | Tha DCC-3116 na neach-dìon beòil ULK1/2. |
CPDA601378 | Orains neo-lacridine | |
CPD112537 | 4H-1,3-Dioxolo [4,5-c] pyrrole-4-carboxylic acid,... | |
CPDP801763 | MC3138 | Tha MC3138 na ghnìomhaiche SIRT5 roghnach. |
CPDP801758 | Chk1-IN-6 | Tha Chk1-IN-6 na neach-dìon tagraiche CHK1 làidir, roghnach agus bith-ruigsinneach. |
CPD113410 | NDI-101150 | Tha NDI-101150 na neach-dìon cumhachdach agus roghnach de HPK1 (cealla progenitor hematopoietic kinase 1). |
CPDA601453 | BMS-986408 | Tha BMS-986408 na neach-dìon dùbailte DGK α / Zeta a tha èifeachdach gu beòil. |
CPDA601445 | AZD0780;EX-A6975; inbhe àrd; laroprovstat | Tha PCSK9-IN-12 na mheasgachadh heteroaromatic. Tha dàimh ceangail aig PCSK9-IN-12 ri PCSK9 le luach Kd<200 nm. Faodar PCSK9-IN-12 a chleachdadh airson sgrùdadh air metabolism cholesterol. |
CPDA601447 | PF07328948 | Tha PF-07328948 na neach-dìon beòil BDK (slabhraidh meurach ketone dehydrogenase kinase). |
CPD112881 | (1S)-2,2,2-trifluoro-1-methylethyl] hydrazine hy... | |
CPD108261 | LOXO-305;LY 3527727; Pirtobrutinib | Tha Pirtobrutinib (LOXO-305) na neach-dìon BTK an ath ghinealach a tha gu math roghnach agus neo-chovalent a dh’ fhaodadh casg a chuir air grunn mhùthaidhean ionadachaidh BTK C481. |
CPD115335 | Luxdegalutamide; ARV-766 | Tha Luxdegalutamide (ARV-766) na inneal èifeachdach beòil hydrolysis pròtain cuimsichte chimeric (PROTAC) ag amas air receptor androgen (AR), a dh'fhaodas mutants co-cheangailte ri strì AR a lughdachadh. |
CPDA601356 | iHSP110-33 | |
CPDP800487 | TNG 462 | Tha TNG-462 na neach-dìon PRMT5 roghnach a tha èifeachdach gu beòil. |
CPDP801649 | 1,2,4-Triazolo[4,3-c] pyrimidine-5,8-diamine, N5... | Tha EED ligand 1 na neach-dìon eadar-mheasgte agus èifeachdach a tha ag amas air fo-aonad EED de methyltransferase PRC2. |
CPDM400208 | 6,7-Difluoro-4(3H)-quinazolinone | |
CPDP801752 | N-(4-quinolinylcarbonyl) Glycine | |
CPDM400190 | Methyl 5-bromo-2-methyl-3-(trifluoromethyl) benz... | |
CPDP800126 | IDE397 (GSK-4362676) | |
CPDP801185 | NST-628 | Tha NST-628 na gel moileciuil slighe MAPK le permeability cnap-starra fuil-eanchainn, a dh’ fhaodadh bacadh a chuir air fosphorylation RAF agus gnìomhachd MEK. |
CPD115153 | NX-2127 | Tha NX-2127 na neach-dìon BTK beòil. |