OTS964
Rincian produk
Tag produk
| Ukuran Pek | Kasadiaan | Harga (USD) |
| 1g | Aya sasayogian | 1750 |
| Langkung Ukuran | Meunang Tanda kutip | Meunang Tanda kutip |
Ngaran Kimia:
(R)-9-(4-(1-(dimethylamino)propan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one
Kode SMILES:
[H]Cl.O=C1NC2=C(C(C3=CC=C([C@@H](C)CN(C)C)C=C3)=C(O)C=C2C)C4=C1SC =C4
Kodeu InChi:
InChI=1S/C23H24N2O2S.ClH/c1-13-11-18(26)19(16-7-5-15(6-8-16)14(2)12-25(3)4)20-17- 9-10-28-22(17)23(27)24-21(13)20;/h5-11,14,26H,12H2,1-4H3,(H,24,27);1H/t14-; /m0./s1
Konci InChi:
YHPWOYBWUWSJDW-UQKRIMTDSA-N
kecap konci:
OTS 964, OTS-964, OTS964, 1338545-07-5
Kalarutan:Leyur dina DMSO
Panyimpenan:0 - 4°C kanggo jangka pondok (poé ka minggu), atanapi -20°C kanggo jangka panjang (bulan)
Katerangan:
OTS964 mangrupakeun inhibitor tina lymphokine-diaktipkeun killer T protéin kinase asal sél (TOPK; IC50 = 28 nM). Ieu husus meungpeuk sitokinesis, ngarah kana apoptosis, dina rentang lega sél kanker. OTS964 induces apoptosis sél kanker paru manusa dina xenografts mouse.
Sasaran: TOPK
