Voruciclib
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
Chemical Name:
2-(2-Chloro-4-(trifluoromethyl)phenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl)-4H-1-benzopyran -4-imwe
SMILES Kodhi:
O=C1C=C(C2=CC=C(C(F)(F)F)C=C2Cl)OC3=C([C@H]4[C@H](CO)N(C)CC4)C (O)=CC(O)=C13
InChi Code:
InChI=1S/C22H19ClF3NO5/c1-27-5-4-12(14(27)9-28)19-15(29)7-16(30)20-17(31)8-18(32-21( 19)20)11-3-2-10(6-13(11)23)22(24,25)26/h2-3,6-8,12,14,28-30H,4-5,9H2, 1H3/t12-,14+/m1/s1
InChi Key:
MRPGRAKIAJJGMM-OCCSQVGLSA-N
Keyword:
P1446A05, P1446A-05, P1446A 05, Voruciclib
Solubility:
Kuchengeta:
Tsanangudzo:
Voruciclib, inozivikanwawo seP1446A-05, iprotein kinase inhibitor yakanangana necyclin-dependent kinase 4 (CDK4) ine inogona kuita antineoplastic chiitiko. CDK4 inhibitor P1446A-05 inonyanya kurambidza CDK4-mediated G1-S chikamu shanduko, kusunga sero bhasikoro uye inhibiting cancer cell kukura. Iyo serine/threonine kinase CDK4 inowanikwa mune yakaoma ine D-mhando G1 cyclins uye ndiyo yekutanga kinase kuti ishandiswe pane mitogenic kukurudzira, kuburitsa masero kubva padanho rakanyarara kupinda muG1/S kukura bhasikoro nhanho; CDK-cyclin complexes yakaratidzwa kune phosphorylate iyo retinoblastoma (Rb) chinyorwa chekunyora mukutanga kweG1, ichibvisa histone deacetylase (HDAC) uye ichivharira kudzvinyirirwa kwezvinyorwa.
Chinangwa: CDK4
