| CAT # | Product Name | Tsanangudzo |
| CPD100464 | Erdafitinib | Erdafitinib, inozivikanwawo seJNJ-42756493, ine simba uye inosarudza nemuromo bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor ine inogona kuita antineoplastic chiitiko. Pamusoro pekutonga nemuromo, JNJ-42756493 inosungira uye inhibits FGFR, iyo inogona kukonzera kuvharwa kweFGFR-yakabatana nechiratidzo chekushandura nzira uye nokudaro kuvharidzirwa kwekuputika kwemasero ekuputika uye kufa kwechirwere chechirwere muFGFR-overexpressing tumor cells. FGFR, yakasimudzwa mune akawanda tumor cell marudzi, ndeye receptor tyrosine kinase yakakosha ku tumor cell kuwanda, kusiyanisa uye kurarama. |
| CPD3618 | TAS-120 | TAS-120 ndeyemuromo bioavailable inhibitor ye fibroblast growth factor receptor (FGFR) ine inogona kuita antineoplastic chiitiko. FGFR inhibitor TAS-120 yakasarudzwa uye isingachinjiki inosunga uye inhibits FGFR, izvo zvingaguma nekudziviswa kwese FGFR-mediated signal transduction nzira uye bundu cell proliferation, uye kuwedzera kwesero kufa muFGFR-overexpressing tumor cells. FGFR ndeye receptor tyrosine kinase yakakosha kune bundu masero kuwanda, kusiyanisa uye kurarama uye kutaura kwayo kunokwidziridzwa mumhando dzakawanda dzebundu cell. |
| CPDB1093 | Derazantinib; ARQ-087 | Derazantinib, inozivikanwawo se ARQ-087, ndeyemuromo bioavailable inhibitor ye fibroblast growth factor receptor (FGFR) ine inogona kuita antineoplastic. |
| CPDB0942 | BLU-554 | BLU-554 inonzi fibroblast growth factor receptor 4 (FGFR4) inhibitor inogona kurapa hepatocellular carcinoma uye cholangiocarcinoma. |
| CPD0999 | H3B-6527 | H3B-6527 (H3 Biomedicine) inosarudza FGFR4 inhibitor ine simba rekurwisa tumour muFGF19 amplified cell lines nemakonzo. |
| CPD0997 | FGF401 | FGF-401 inhibitor yeFGFR4 yakatorwa kubva patent WO2015059668A1, muenzaniso wekomboni 83; ine IC50 ye1.9 nM. |
| CPDB0053 | AZD4547 | AZD 4547 is selective inhibitor ye fibroblast growth factor receptor (FGFR) tyrosine kinase ine IC50 tsika dze 0.2, 2.5, uye 1.8 nM yeFGFR1, 2, uye 3, zvichienderana. |
| CPD3610 | BLU-9931 | BLU9931 ine simba, inosarudza, uye isingadzokeri FGFR4 inhibitor ine IC50 ye3 nM, inenge 297-, 184-, uye 50-fold selectivity pamusoro peFGFR1/2/3, zvichiteerana. |
