EGFR

CAT # Product Name Tsanangudzo
CPD100230 JBJ-04-125-02 R-isomer
CPD3232 NTN21277 NTN21277, inozivikanwawo seGefitinib-based PROTAC 3 inonzi VHL-recruiting PROTAC inokonzera kusvibiswa kweEGFR neEGFR mutants ine DC50 ye11.7 nM uye 22.3 nM yeHCC827 cell (Exon 19 del) uye H3255R cell (L8255R).
CPDB3615 Nazartinib; EGF816; NVS-816 Nazartinib, inozivikanwawo seEGF816 uye NVS-816, inowanikwa nemuromo, isingadzokerike, yechitatu-chizvarwa, inosarudzika epidermal growth factor receptor (EGFR) inhibitor, ine inogona kuita antineoplastic.
CPDB0934 EAI-045 EAI045 ia ine simba uye inosarudza EGFR inhbitor. EAI045 inonangwa yakasarudza EGFR isingaite mushonga asi inochengetedza mhuka yemusango inogamuchira. EAI045 inhibits L858R/T790M-mutant EGFR ine yakaderera-nanomolar potency mu biochemical assays.
CPDB0101 Poziotinib Magadzirirwo ane poziotinib ari pasi pekuongororwa mumakiriniki ekuedzwa kwekurapa kweEGFR-mutant lung adenocarcinoma.
CPDB0137 Osimertinib Mesylate Osimertinib, inozivikanwawo semereletinib uye AZD-9291, chizvarwa chechitatu cheEGFR inhibitor, yakaratidza chivimbiso muzvidzidzo zvepakutanga uye inopa tariro kune varwere vane kenza yemapapu yepamusoro iyo yave isingagadziriki kune EGFR inhibitors iripo.
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