in vitro Pharmacokinetic Assays

Yedu pharmacokinetic timu inoshandira preclinical kusimudzira, DMPK kuongorora uye IND kunyoreswa. Isu takagadzira yakasanganiswa in vitro & mu vivo yekuongorora tekinoroji tekinoroji mukutsigira kuwanikwa kwezvinodhaka nekusimudzira. Caerulum Pharma inopa inoshanduka uye yakasarudzika sevhisi kune inoshanda uye inodhura-inodhura DMPK mhinduro dzekufambisa tsvakiridzo yako kumberi.

1.Zvikamu zvekudzidza

Madiki mamorekuru, zvigadzirwa zvechisikigo, polypeptides.

2.Available services

Plasma/tissue protein binding assay

Plasma kune ropa reshiyo

Chiropa microsomal metabolic kugadzikana

Kugadzikana mumotokari uye plasma

Metabolite kuzivikanwa

CYP kuita phenotyping

CYP inhibition

3.Mukuvaka

Hepatocyte Induction

Caco-2 Permeability

UGT maitiro phenotyping


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