Alvocidib
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
Chemical Name:
2-(2-chlorophenyl)-5,7-dihydroxy-8-((3R,4S)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one
SMILES Kodhi:
O=C1C=C(C2=CC=CC=C2Cl)OC3=C([C@H]4[C@@H](O)CN(C)CC4)C(O)=CC(O)=C13
InChi Code:
InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28- 21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12- ,17+/m1/s1
InChi Key:
BIIVYFLTOXDAOV-PXAZEXFGSA-N
Keyword:
L 86-8275; L-868275; L 868275; L868275; HMR 1274; HMR-1274; HMR1274; Flavoperidol; Alvocidib
Solubility:
Kuchengeta:
Tsanangudzo:
Alvocidib is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. Se inhibitor ye cyclin-inotsamira kinase, alvocidib induces cell cycle kusungwa nekudzivirira phosphorylation ye cyclin-dependent kinases (CDKs) uye nekudzika-inotonga cyclin D1 uye D3 kutaura, zvichiita kuti G1 cell cycle kusungwa uye apoptosis. Uyu mumiririri zvakare inokwikwidza inhibitor yeadenosine triphosphate basa. Tarisa uone kushanda kwekiriniki miedzo kana kuvharwa kwekiriniki miedzo uchishandisa mumiririri uyu.
Chinangwa: CDK
