SEL120-34A
Product Detail
Product Tags
Pack Saizi | Kuwanikwa | Mutengo (USD) |
Chemical Name:
7,8-Dibromo-9-methyl-2-piperazin-1-yl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline Hydrochloride
SMILES Kodhi:
CC1=C(Br)C(Br)=C2CCCN3C2=C1N=C3N4CCNCC4.[H]Cl
InChi Code:
InChI=1S/C15H18Br2N4.ClH/c1-9-11(16)12(17)10-3-2-6-21-14(10)13(9)19-15(21)20-7-4- 18-5-8-20;/h18H,2-8H2,1H3;1H
InChi Key:
GQXLWUCQESKBSC-UHFFFAOYSA-N
Keyword:
SEL120-34A; SEL 120-34A; SEL-120-34A; SEL12034A; SEL 12034A; SEL-12034A
Solubility:
Kuchengeta:
Tsanangudzo:
SEL120-34A ine simba uye inosarudza CDK8 inhibitor inoshanda muAML maseru ane yakakwira serine phosphorylation yeSTAT1 uye STAT5 transactivation domains. EL120-34A inhibits phosphorylation yeSTAT1 S727 uye STAT5 S726 mumasero ekenza mu vitro. Sezvineiwo, kudzorwa kweSTATs- uye NUP98-HOXA9- inotsamira kunyorwa yakaonekwa seyakanyanya nzira yekuita mu vivo.
Chinangwa: CDK8