SEL120-34A

SEL120-34A
  • Zita:SEL120-34A
  • Catalog Nhamba:CPD100910
  • Nhamba yeCAS:1609522-33-9 (yemahara base) 1609452-30-3 (HCl)
  • Molecular Weight:450.599
  • Chemical Formula:C15 H19 Br2 Cl N4
  • Kutsvakurudza kwesayenzi chete, kwete kuvarwere.

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    Chemical Name:

    7,8-Dibromo-9-methyl-2-piperazin-1-yl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline Hydrochloride

    SMILES Kodhi:

    CC1=C(Br)C(Br)=C2CCCN3C2=C1N=C3N4CCNCC4.[H]Cl

    InChi Code:

    InChI=1S/C15H18Br2N4.ClH/c1-9-11(16)12(17)10-3-2-6-21-14(10)13(9)19-15(21)20-7-4- 18-5-8-20;/h18H,2-8H2,1H3;1H

    InChi Key:

    GQXLWUCQESKBSC-UHFFFAOYSA-N

    Keyword:

    SEL120-34A; SEL 120-34A; SEL-120-34A; SEL12034A; SEL 12034A; SEL-12034A

    Solubility: 

    Kuchengeta: 

    Tsanangudzo:

    SEL120-34A ine simba uye inosarudza CDK8 inhibitor inoshanda muAML maseru ane yakakwira serine phosphorylation yeSTAT1 uye STAT5 transactivation domains. EL120-34A inhibits phosphorylation yeSTAT1 S727 uye STAT5 S726 mumasero ekenza mu vitro. Sezvineiwo, kudzorwa kweSTATs- uye NUP98-HOXA9- inotsamira kunyorwa yakaonekwa seyakanyanya nzira yekuita mu vivo.

    Chinangwa: CDK8


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