THZ2
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
| 100mg | Mudura | 500 |
| 500mg | Mudura | 800 |
| 1g | Mudura | 1200 |
| Mamwe Saizi | Wana MaQuotes | Wana MaQuotes |
Chemical Name:
N- [[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-3-[[(E)-4-(dimethylamino)asi-2- enoyl]amino]benzamide
SMILES Kodhi:
O=C(NC1=CC=CC(NC2=NC=C(Cl)C(C3=CNC4=C3C=CC=C4)=N2)=C1)C5=CC=CC(NC(/C=C/CN (C)C)=O)=C5
InChi Code:
InChI=1S/C31H28ClN7O2/c1-39(2)15-7-14-28(40)35-21-9-5-8-20(16-21)30(41)36-22-10-6- 11-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-13-4-3-12-24(25)27/h3- 14,16-19,33H,15H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b14-7+
InChi Key:
FONRCZUZCHXWBD-VGOFMYFVSA-N
Keyword:
THZ-2, THZ 2, THZ2, 1604810-84-5
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).
Tsanangudzo:
THZ2, analogi yeTHZ1, ine mukana wekurapa Triple-negative cancer cancer (TNBC), ine simba uye inosarudza CDK7 inhibitor inokunda kusagadzikana kweTHZ1 in vivo. IC50: CDK7= 13.9 nM; TNBC maseru= 10 nM
Chinangwa: CDK
