MC180295
Kutsvakurudza kwesayenzi chete, kwete kuvarwere.
Product Detail
Product Tags
Pack Saizi | Kuwanikwa | Mutengo (USD) |
Chemical Name:
Rel-(4-amino-2-(((2S)-bicyclo[2.2.1]heptan-2-yl)amino)thiazol-5-yl)(2-nitrophenyl)methanone
SMILES Kodhi:
O=C(C1=C(N)N=C(N[C@@H]2C(C3)CCC3C2)S1)C4=CC=CC=C4[N+]([O-])=O
InChi Code:
InChI=1S/C17H18N4O3S/c18-16-15(14(22)11-3-1-2-4-13(11)21(23)24)25-17(20-16)19-12-8- 9-5-6-10(12)7-9/h1-4,9-10,12H,5-8,18H2,(H,19,20)/t9?,10?,12-/m0/s1
InChi Key:
JRNXAQINDCOHGS-CBINBANVSA-N
Keyword:
Solubility:
Kuchengeta:
Tsanangudzo:
MC180295 inonyanya kusarudza CDK9 inhibitor (IC50 = 5 nM). (MC180295 ine yakakura anti-cancer chiitiko mu vitro uye inoshanda mu vivo cancer modhi. Uyezve, CDK9 inhibition inosimudzira kune immune checkpoint inhibitor α-PD-1 mu vivo, zvichiita kuti ive chinangwa chakanakisa che epigenetic kurapa kenza.
Chinangwa: CDK9