CP-456773 sodium
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
| 100mg | Mudura | 500 |
| 500mg | Mudura | 800 |
| 1g | Mudura | 1200 |
| Mamwe Saizi | Wana MaQuotes | Wana MaQuotes |
Chemical Name:
sodium ((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)(4-(2-hydroxypropan-2-yl)furan-2-yl)sulfonyl)amide
SMILES Kodhi:
O=S(C1=CC(C(C)(O)C)=CO1)([N-]C(NC2=C3CCCC3=CC4=C2CCC4)=O)=O.[Na+]
InChi Code:
InChI=1S/C20H24N2O5S.Na/c1-20(2,24)14-10-17(27-11-14)28(25,26)22-19(23)21-18-15-7-3- 5-12(15)9-13-6-4-8-16(13)18;/h9-11,24H,3-8H2,1-2H3,(H2,21,22,23);/q; +1/p-1
InChi Key:
LFQQNXFKPNZRFT-UHFFFAOYSA-M
Keyword:
MCC950, MCC 950, MCC-950, CP-45677, CP45677, CP 45677, CRID-3, CRID3, CRID 3, CP-456773 sodium munyu, Cytokine release inhibitory drug 3, 256373-9
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).
Tsanangudzo:
CP-456773, inozivikanwawo seMCC950 uye CRID3, ine simba uye inosarudza cytokine release inhibitor uye NLRP3 inflammasome inhibitor yekurapa zvirwere zvinopisa. CP-456773 inhibits interleukin 1β (IL-1β) secretion uye caspase 1 kushandiswa. MCC950 yakavharira canonical uye noncanonical NLRP3 activation pane nanomolar concentrations. MCC950 yakanyatso inhibited activation yeNLRP3 asi kwete iyo AIM2, NLRC4 kana NLRP1 inflammasomes. MCC950 yakaderedza interleukin-1β (IL-1β) kugadzirwa mu vivo uye yakaderedza kuoma kwekuedza autoimmune encephalomyelitis (EAE), chirwere chechirwere che multiple sclerosis. MCC950 inogona kurapa kweNLRP3-yakabatana syndromes, kusanganisira autoinflammatory uye autoimmune zvirwere, uye chishandiso chekuwedzera kudzidza kweNLRP3 inflammasome muhutano hwevanhu uye chirwere.
Chinangwa: NLRP3
