Adavivint

Adavivint
  • Zita:Adavivint; SM04690
  • Catalog Nhamba:CPDD1633
  • Nhamba yeCAS:1467093-03-3
  • Molecular Weight:505.55
  • Chemical Formula:C29H24FN7O
  • Kutsvakurudza kwesayenzi chete, kwete kuvarwere.

    Product Detail

    Product Tags

    Pack Saizi Kuwanikwa Mutengo (USD)
    100mg Mudura 500
    500mg Mudura 800
    1g Mudura 1200
    Mamwe Saizi Wana MaQuotes Wana MaQuotes

    Chemical Name:

    N-(5-{3--[7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3 -methylbutanamide

    SMILES Kodhi:

    CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN= C1)=O

    InChi Code:

    InChI=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28( 37-36-24)29-34 -25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9-16H,8H2,1-2H3,( H,33,38)(H,34,35)(H,36,37)

    InChi Key:

    AQDWDWAYVBQMAM-UHFFFAOYSA-N

    Keyword:

    Adavivint, SM04690, SM-04690, SM 04690, 1467093-03-3

    Solubility:Soluble muDMSO

    Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).

    Tsanangudzo:

    Novel diki molecule Wnt pathway inhibitor ine EC50 ye3 nM in vitro; inokonzera kusiyanisa kwehMSC kuva yakakura, inoshanda chondrocytes uye inoderedza cartilage catabolic marker mazinga; inovandudza zvakanyanya Osteoarthritis Research Society International (OARSI) histology zvibodzwa uye biomarker mune rodent OA modhi.

    Chinangwa: WNT


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