RGX-104 HCl
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
| 100mg | Mudura | 500 |
| 500mg | Mudura | 800 |
| 1g | Mudura | 1200 |
| Mamwe Saizi | Wana MaQuotes | Wana MaQuotes |
Chemical Name:
(R) -2 -- [3- [[2-Chloro-3- (trifluoromethyl) benzyl] (2,2-diphenylethyl) amino] -3-methylpropoxy]phenyl]acetic acid hydrochloride
SMILES Kodhi:
O=C(O)CC1=CC=CC(OCC[C@H](N(CC2=CC=CC(C(F)(F)F)=C2Cl)CC(C3=CC=CC=C3)C4 =CC=CC=C4)C)=C1.[H]Cl
InChi Code:
InChI=1S/C34H33ClF3NO3.ClH/c1-24(18-19-42-29-16-8-10-25(20-29)21-32(40)41)39(22-28-15-9- 17-31(33(28)35)34(36 ,37)38)23-30(26-11-4-2-5-12-26)27-13-6-3-7-14-27;/h2-17,20,24,30H,18- 19,21-23H2,1H3,(H,40,41);1H/t24-;/m1./s1
InChi Key:
LCMIYQOJZLRHTO-GJFSDDNBSA-N
Keyword:
RGX-104 HCl, RGX-104, RGX104, RGX 104, 610318-03-1
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).
Tsanangudzo:
RGX-104 chiropa X receptor beta agonist ine zvinogona immunomodulating uye antineoplastic zviitiko. Pamusoro pekutonga nemuromo, RGX-104 inosarudza uye inosunga kuLXRbeta, nekudaro ichimisikidza LXRbeta-mediated siginecha, zvichitungamira mukunyorwa kwemamwe magene ekudzvanya bundu uye kudzikiswa kwemamwe majini anosimudzira bundu. Izvi zvinonyanya kuita kuti kutaura kweapolipoprotein E (ApoE), bundu rinodzvanya puroteni, mumaseru ebundu uye mamwe masero edziviriro. Izvi zvinomutsa immune system yemukati, zvichikonzera kupera kwema immunosuppressive myeloid-derived suppressor cell (MDSCs), tumor cell uye endothelial masero mune bundu microenvironment. Izvi zvinodzoreredza kudzivirira kudzivirira, kunowedzera anti-tumor immune mhinduro uye inhibisa kuwanda kwebundu masero.
Chinangwa: LXRbeta
