ARS-1630

ARS-1630
  • Igoa:ARS-1630
  • Numera fa'amaumauga:CPDB2016
  • Numera CAS:1698055-86-5
  • Molecular Weight:430.84
  • Fua Fa'atatau ole vaila'au:C21H17ClF2N4O2
  • Mo na'o su'esu'ega fa'asaienisi, ae le mo gasegase.

    Fa'amatalaga Oloa

    Faailoga o oloa

    Tele o le afifi Avanoa Tau (USD)
    100mg E tele 800
    500mg E tele 1500
    1g E tele 2000
    Tele Tele Maua Upusii Maua Upusii

    Igoa vaila'au:

    (R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl) piperazin-1-yl) prop-2-en-1-one

    SMILES Code:

    "C=CC(N1CCN(C2=C3C=C(Cl)[C@@]([C@@]4=C(O)C=CC=C4F)=C(F)C3=NC=N2)CC1 )=O.[R]

    InChi Code:

    InChi Key:

    upu autu:

    ARS1630, ARS 1630, ARS-1630, 1698055-86-5

    Solubility:Solu i le DMSO

    Teuina:0 - 4°C mo taimi pupuu (aso i vaiaso), po'o le -20°C mo taimi uumi (masina)

    Fa'amatalaga:

    ARS-1630 o le R-conformational atropisomer o ARS-1620, 1,000-gaiga itiiti malosi nai lo ARS-1620 (1.2 ± 0.6 M-1s-1) ma o lea e galue o se tuufaatasiga tulaga ese le toaga.

    Sini: KRAS (K-Ras G12C)


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