PUSI # | Igoa Oloa | Fa'amatalaga |
CPD111306 | 7-bromo-2,4,6-trichloro-8-fluoroquinazoline | |
CPD113109 | ARS-1323-Alkyne | ARS-1323-alkyne, o se sui-II taga (S-IIP) inhibitor |
CPDP801183 | VVD-214;RO7589831;VVD-133214 | VVD-214 o se WRN helicase lethal allosteric inhibitor. |
CPDP801366 | Inlexisertib;DCC-3116 | O le DCC-3116 o se fa'agata ULK1/2 fa'amalosi tautala. |
CPDA601378 | Nonylacridine moli | |
CPD112537 | 4H-1,3-Dioxolo[4,5-c]pyrrole-4-carboxylic acid,... | |
CPDP801763 | MC3138 | MC3138 o se SIRT5 activator filifilia. |
CPDP801758 | Chk1-IN-6 | O le Chk1-IN-6 ose fa'atosina malosi, filifili, ma e mafai ona tu'u gutu ole CHK1 fa'aitaga sui tauva. |
CPD113410 | NDI-101150 | O le NDI-101150 o se inhibitor malosi ma filifili ole HPK1 (hematopoietic progenitor cell kinase 1). |
CPDA601453 | BMS-986408 | O le BMS-986408 o se fa'ailo fa'agata lua DGK α/Zeta. |
CPDA601445 | AZD0780;EX-A6975;laroprovstatum; laroprovstat | PCSK9-IN-12 o se faʻalapotopotoga heteroaromatic. PCSK9-IN-12 o loʻo i ai le sootaga vavalalata mo PCSK9 ma le tau Kd<200 nM. PCSK9-IN-12 e mafai ona faʻaaogaina mo le suʻesuʻeina o le cholesterol metabolism. |
CPDA601447 | PF07328948 | PF-07328948 ose BDK aoga (branched chain ketone dehydrogenase kinase) inhibitor. |
CPD112881 | (1S)-2,2,2-trifluoro-1-methylethyl]hydrazine hy... | |
CPD108261 | LOXO-305;LY 3527727;Pirtobrutinib | Pirtobrutinib (LOXO-305) o se mea e sili ona filifilia ma e le o se faʻaogaina o le isi augatupulaga BTK inhibitor e mafai ona faʻalavelaveina suiga eseese o le BTK C481. |
CPD115335 | Luxdegalutamide; ARV-766 | O le Luxdegalutamide (ARV-766) o se polotini e fa'atatau i le hydrolysis e fa'atatau i le chimeric (PROTAC) e fa'atatau i le androgen receptor (AR), lea e mafai ona fa'aleagaina ai mutants e feso'ota'i ma AR. |
CPDA601356 | iHSP110-33 | |
CPDP800487 | TNG462 | O le TNG-462 o se fa'aitaga PRMT5 filifilia tautala lelei. |
CPDP801649 | 1,2,4-Triazolo[4,3-c]pyrimidine-5,8-diamine, N5... | O le EED ligand 1 o se inhibitor eseese ma aoga e faʻatatau i le EED subunit o le methyltransferase PRC2. |
CPDM400208 | 6,7-Difluoro-4(3H)-quinazolinone | |
CPDP801752 | N-(4-quinolinylcarbonyl)Glycine | |
CPDM400190 | Methyl 5-bromo-2-methyl-3-(trifluoromethyl)benz... | |
CPDP800126 | IDE397 (GSK-4362676) | |
CPDP801185 | NST-628 | O le NST-628 o le MAPK molecular gel mole faʻatasi ma le faʻaogaina o le paʻu toto-faiʻai, lea e mafai ona faʻalavelaveina le phosphorylation RAF ma le faʻagaoioia MEK. |
CPD115153 | NX-2127 | NX-2127 ose BTK inhibitor tautala lelei. |