ARS-1323

ARS-1323
  • Igoa:ARS-1323
  • Numera fa'amaumauga:CPDB2015
  • Numera CAS:1698024-73-5
  • Molecular Weight:430.84
  • Fua Fa'atatau ole vaila'au:C21H17ClF2N4O2
  • Mo na'o su'esu'ega fa'asaienisi, ae le mo gasegase.

    Fa'amatalaga Oloa

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    500mg E tele 800
    1g E tele 1200
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    Igoa vaila'au:

    1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl) piperazin-1-yl) prop-2-en-1-one

    SMILES Code:

    O=C(C=C)N1CCN(C2=NC=NC3=C2C=C(Cl)C(C4=C(O)C=CC=C4F)=C3F)CC1

    InChi Code:

    InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17( 19(24)20(12)25-11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2

    InChi Key:

    ZRPZPNYZFSJUPA-UHFFFAOYSA-N

    upu autu:

    ARS1323,ARS 1323,ARS-1323, 1698024-73-5

    Solubility:Solu i le DMSO

    Teuina:0 - 4°C mo taimi pupuu (aso i vaiaso), po'o le -20°C mo taimi uumi (masina)

    Fa'amatalaga:

    ARS-1323 o se fa'amaufa'ailoga fou o mutant K-ras G12C maua mai pateni WO 2015054572 A1. IC50 & Sini: K-Ras G12C

    Sini: KRAS (K-Ras G12C)


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