Chithunzi cha SEL120-34A

Chithunzi cha SEL120-34A
  • Dzina:Chithunzi cha SEL120-34A
  • Catalog No.:CPD100910
  • Nambala ya CAS:1609522-33-9 (m'munsi mwaulere) 1609452-30-3 (HCl)
  • Kulemera kwa Molecular:450.599
  • Chemical formula:C15 H19 Br2 Cl N4
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    Paketi Kukula Kupezeka Mtengo (USD)

    Dzina la Chemical:

    7,8-Dibromo-9-methyl-2-piperazin-1-yl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline Hydrochloride

    SMILES Kodi:

    CC1=C(Br)C(Br)=C2CCCN3C2=C1N=C3N4CCNCC4.[H]Cl

    InChi kodi:

    InChI=1S/C15H18Br2N4.ClH/c1-9-11(16)12(17)10-3-2-6-21-14(10)13(9)19-15(21)20-7-4- 18-5-8-20;/h18H,2-8H2,1H3;1H

    InChi Key:

    GQXLWUCQESKBSC-UHFFFAOYSA-N

    Mawu ofunika:

    SEL120-34A; SEL 120-34A; SEL-120-34A; SEL12034A; SEL 12034A; SEL-12034A

    Kusungunuka: 

    Posungira: 

    Kufotokozera:

    SEL120-34A ndi CDK8 inhibitor yamphamvu komanso yosankha yogwira ntchito m'maselo a AML okhala ndi serine phosphorylation ya STAT1 ndi STAT5 transactivation domains. EL120-34A imalepheretsa phosphorylation ya STAT1 S727 ndi STAT5 S726 m'maselo a khansa mu vitro. Nthawi zonse, kuwongolera kwa STATs- ndi NUP98-HOXA9- kutengera zolembera kwawonedwa ngati njira yayikulu yochitira zinthu mu vivo.

    Cholinga: CDK8


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