MPAKA # | Dzina lazogulitsa | Kufotokozera |
Chithunzi cha CPD1573 | GDC-0077 | GDC-0077 ndi PI3K inhibitor yomwe imapezeka pakamwa yomwe ingathe kuchitapo kanthu. |
Chithunzi cha CPD1022 | IPI-549 | IPI549 ndi PI3Kγ Inhibitor yamphamvu komanso yosankha yokhala ndi IC50 ya 16 nM. |
Chithunzi cha CPDD3857 | GDC-0326 | GDC-0326 ndi inhibitor yamphamvu komanso yosankha ya α-Isoform ya Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). GDC-0326 imakwaniritsa kusankhidwa kwapamwamba kwambiri kuposa ma kinase ena. GDC-0326 ili ndi plasma yotsika CL mwa anthu. |
Chithunzi cha CPDB0202 | AZD8186 | AZD8186 ndi inhibitor ya beta isoform ya phosphoinositide-3 kinase (PI3K), yokhala ndi ntchito yoletsa antiineoplastic. |
Mtengo wa CPDB1536 | PQR530 | PQR530 ndi yamphamvu kwambiri yapawiri pan-PI3K/mTORC1/2 inhibitor. |
Mtengo wa CPDB1573 | GDC-0077 | GDC-0077 ndi pakamwa komanso kusankha PI3K inhibitor (IC50 = 0.038 + 0.003 nM) ndi> 300-kusankha ma Class I PI3K isoforms. |