Chithunzi cha PI3K

MPAKA # Dzina lazogulitsa Kufotokozera
Chithunzi cha CPD1573 GDC-0077 GDC-0077 ndi PI3K inhibitor yomwe imapezeka pakamwa yomwe ingathe kuchitapo kanthu.
Chithunzi cha CPD1022 IPI-549 IPI549 ndi PI3Kγ Inhibitor yamphamvu komanso yosankha yokhala ndi IC50 ya 16 nM.
Chithunzi cha CPDD3857 GDC-0326 GDC-0326 ndi inhibitor yamphamvu komanso yosankha ya α-Isoform ya Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). GDC-0326 imakwaniritsa kusankhidwa kwapamwamba kwambiri kuposa ma kinase ena. GDC-0326 ili ndi plasma yotsika CL mwa anthu.
Chithunzi cha CPDB0202 AZD8186 AZD8186 ndi inhibitor ya beta isoform ya phosphoinositide-3 kinase (PI3K), yokhala ndi ntchito yoletsa antiineoplastic.
Mtengo wa CPDB1536 PQR530 PQR530 ndi yamphamvu kwambiri yapawiri pan-PI3K/mTORC1/2 inhibitor.
Mtengo wa CPDB1573 GDC-0077 GDC-0077 ndi pakamwa komanso kusankha PI3K inhibitor (IC50 = 0.038 + 0.003 nM) ndi> 300-kusankha ma Class I PI3K isoforms.
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