| MPAKA # | Dzina lazogulitsa | Kufotokozera |
| CPD100230 | JBJ-04-125-02 R-isomer | |
| Chithunzi cha CPD3232 | NTN21277 | NTN21277, yomwe imadziwikanso kuti Gefitinib-based PROTAC 3 ndi VHL-recruiting PROTAC yomwe imapangitsa kuwonongeka kwa EGFR ndi EGFR mutants ndi DC50 ya 11.7 nM ndi 22.3 nM ya HCC827 cell (Exon 19 del) ndi H3258R cell (L8255R). |
| Chithunzi cha CPDB3615 | Nazartinib; EGF816; Mtengo wa NVS-816 | Nazartinib, yomwe imadziwikanso kuti EGF816 ndi NVS-816, imapezeka pakamwa, yosasinthika, ya m'badwo wachitatu, mutant-selective epidermal growth factor receptor (EGFR) inhibitor, yomwe ingathe kuchitapo kanthu. |
| Mtengo wa CPDB0934 | EAI-045 | EAI045 ia wamphamvu komanso kusankha EGFR inhbitor. EAI045 ikufuna kusankha zosintha za EGFR zosamva mankhwala koma zimateteza zolandilira zakuthengo. EAI045 imaletsa L858R/T790M-mutant EGFR yokhala ndi mphamvu yotsika ya nanomolar pakuyesa kwachilengedwe. |
| Chithunzi cha CPDB0101 | Poziotinib | Mapangidwe okhala ndi poziotinib akufufuzidwa m'mayesero azachipatala ochizira EGFR-mutant lung adenocarcinoma. |
| Chithunzi cha CPDB0137 | Osimertinib Mesylate | Osimertinib, yomwe imadziwikanso kuti mereletinib ndi AZD-9291, ndi EGFR inhibitor ya m'badwo wachitatu, inasonyeza lonjezo mu maphunziro a preclinical ndipo imapereka chiyembekezo kwa odwala omwe ali ndi khansa yapamwamba ya m'mapapo yomwe yayamba kugonjetsedwa ndi EGFR inhibitors. |
