MPAKA # | Dzina lazogulitsa | Kufotokozera |
Mtengo wa CPDB1974 | GSK-461364 | GSK461364 modalira mlingo imayimitsa kuyendetsa njinga m'maselo a khansa omwe akuchulukirachulukira ndipo, pamilingo yayikulu, imayambitsa apoptosis. Zikuwoneka kuti ndizothandiza kwambiri polimbana ndi zotupa zopanda p53 ndipo zimatha kuwoloka chotchinga chamagazi-muubongo. GSK461364 imagwira ntchito mu vivo, kupangitsa kuletsa kukula kwa chotupa kapena kuchedwa kwakukula mumitundu ya xenograft mu mbewa. |