| MPAKA # | Dzina lazogulitsa | Kufotokozera |
| Chithunzi cha CPD100464 | Erdafitinib | Erdafitinib, yomwe imadziwikanso kuti JNJ-42756493, ndi yamphamvu komanso yosankha pamlomo bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor yomwe ingakhale ndi ntchito ya antineoplastic. Pogwiritsa ntchito pakamwa, JNJ-42756493 imamangiriza ndikuletsa FGFR, zomwe zingayambitse kulepheretsa njira zotumizira zizindikiro zokhudzana ndi FGFR ndipo motero kulepheretsa kufalikira kwa maselo a chotupa ndi imfa ya maselo a chotupa mu FGFR-overexpressing chotupa maselo. FGFR, yokhazikika mumitundu yambiri yama cell chotupa, ndi receptor tyrosine kinase yofunikira pakuchulukira kwa maselo a chotupa, kusiyanitsa ndi kupulumuka. |
| Chithunzi cha CPD3618 | TAS-120 | TAS-120 ndi orally bioavailable inhibitor ya fibroblast growth factor receptor (FGFR) yokhala ndi ntchito yoletsa antiineoplastic. FGFR inhibitor TAS-120 mosankha komanso mosasinthika imamangiriza ndi kuletsa FGFR, zomwe zingapangitse kuletsa kwa njira yopatsira ma siginecha ya FGFR ndi kuchuluka kwa maselo otupa, komanso kuchuluka kwa kufa kwa maselo mu FGFR-ma cell chotupa ochulukirapo. FGFR ndi receptor tyrosine kinase yofunikira pakuchulukira kwa maselo a chotupa, kusiyanitsa ndi kupulumuka ndipo mawonekedwe ake amayendetsedwa mumitundu yambiri yama cell chotupa. |
| Mtengo wa CPDB1093 | Derazantinib; Chithunzi cha ARQ-087 | Derazantinib, yomwe imadziwikanso kuti ARQ-087, ndi inhibitor yapakamwa ya bioavailable ya fibroblast growth factor receptor (FGFR) yokhala ndi zochita za antiineoplastic. |
| Mtengo wa CPDB0942 | BLU-554 | BLU-554 ndi fibroblast growth factor receptor 4 (FGFR4) inhibitor yomwe ingathe kuchiza hepatocellular carcinoma ndi cholangiocarcinoma. |
| CPD0999 | H3B-6527 | H3B-6527 (H3 Biomedicine) ndiwosankha kwambiri FGFR4 inhibitor yokhala ndi zochita zamphamvu zotsutsana ndi zotupa mu FGF19 amplified cell lines ndi mbewa. |
| CPD0997 | Chithunzi cha FGF401 | FGF-401 ndi inhibitor ya FGFR4 yotengedwa ku patent WO2015059668A1, pawiri chitsanzo 83; ili ndi IC50 ya 1.9 nM. |
| Mtengo wa CPDB0053 | AZD4547 | AZD 4547 ndi inhibitor yosankha ya fibroblast growth factor receptor (FGFR) tyrosine kinase yokhala ndi IC50 yamtengo wapatali ya 0.2, 2.5, ndi 1.8 nM ya FGFR1, 2, ndi 3, motsatira. |
| Chithunzi cha CPD3610 | BLU-9931 | BLU9931 ndi yamphamvu, yosankha, komanso yosasinthika FGFR4 inhibitor yokhala ndi IC50 ya 3 nM, pafupifupi 297-, 184-, ndi 50-fold selectivity pa FGFR1/2/3, motsatana. |
