mu vivo Pharmacokinetic Assays

Gulu lathu la pharmacokinetic limakhazikika pakukula kwachipatala, kuwunika kwa DMPK ndi kulembetsa kwa IND. Tidakhazikitsa nsanja yophatikizika ya in vitro & in vivo screening kuti ithandizire kupeza ndi chitukuko cha mankhwala. Caerulum Pharma imapereka chithandizo chosinthika komanso chamunthu payekha pamayankho a DMPK ogwira mtima komanso otsika mtengo.

1.Zigawo zophunzirira

Mamolekyu ang'onoang'ono, zinthu zachilengedwe, ma polypeptides.

2.Available mautumiki

Kuwunika mwachangu kwa PK kudzera m'njira zosiyanasiyana zoyang'anira mitundu ya makoswe komanso yopanda makoswe, monga mbewa, makoswe, agalu ndi nyani.

Kugawa minofu

Excretion ndi misa balance

CSF sampling ndi BBB kulowa

Kukula kwa njira zowunikira mu biological matrix

Kusanthula kachulukidwe kwa zitsanzo zosiyanasiyana zamoyo

Kukonza ndi kutumiza deta

3.DMPK yokhudzana ndi kapangidwe ka protocol ndi kaphatikizidwe potengera zomwe zafotokozedwa pamaphunziro.


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