Gulu lathu la pharmacokinetic limakhazikika pakukula kwachipatala, kuwunika kwa DMPK ndi kulembetsa kwa IND. Tidakhazikitsa nsanja yophatikizika ya in vitro & in vivo screening kuti ithandizire kupeza ndi chitukuko cha mankhwala. Caerulum Pharma imapereka chithandizo chosinthika komanso chamunthu payekha pamayankho a DMPK ogwira mtima komanso otsika mtengo kuti apititse patsogolo kafukufuku wanu.
1.Zigawo zophunzirira
Mamolekyu ang'onoang'ono, zinthu zachilengedwe, ma polypeptides.
2.Available mautumiki
Kuyesa kwa mapuloteni a Plasma / minofu
Chiyerekezo cha plasma ndi magazi
Chiwindi microsomal metabolic bata
Kukhazikika kwagalimoto ndi plasma
Chizindikiro cha metabolite
CYP reaction phenotyping
Kuletsa kwa CYP
3.Kumanga
Hepatocyte Induction
Caco-2 Permeability
UGT reaction phenotyping