T-26c

Ingoa matū:

4-(((2-((3-methoxybenzyl)carbamoyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl)methoxy)methyl)waikawa benzoic

Waehere SMILES:

O=C(O)C1=CC=C(COCC2=CSC(N=C(C(NCC3=CC=CC(OC)=C3)=O)N4)=C2C4=O)C=C1

Waehere InChi:

InChI=1S/C24H21N3O6S/c1-32-18-4-2-3-15(9-18)10-25-22(29)20-26-21(28)19-17(13-34-23( 19)27-20)12-33-11-14-5-7-16(8-6-14)24(30)31/h2-9,13H,10-12H2,1H3,(H,25,29 )(H,30,31)(H,26,27,28)

Kī InChi:

CDQRIIUMNLMHRH-UHFFFAOYSA-N

Kupumatua:

T-26c, T26c, T 26c, 869296-13-9

Wairewa:Wairewa i roto i te DMSO

Rokiroki:0 - 4°C mo te wa poto (ra ki nga wiki), -20°C ranei mo te wa roa (marama).

Whakaahuatanga:

Ko te T-26c he tino kaha, he whiriwhiri me te pūtau-permeable matrix metalloproteinases 13 (MMP-13) aukati. Ko te T-26c ka aukati i te pakaru o te collagen i roto i te IL-1b me te oncostatin M i whakaihiihihia te kaata.

Whāinga: MMP-13