| CAT # | Ingoa Hua | Whakaahuatanga |
| CPD100464 | Erdafitinib | Ko Erdafitinib, e mohiotia ana ko JNJ-42756493, he kaha me te whiriwhiri i te koiora-a-waha, te pan fibroblast growth factor receptor (FGFR) aukati me te mahi antineoplastic pea. I runga i te whakahaere a-waha, ka herea e JNJ-42756493 me te whakakore i te FGFR, ka puta pea te whakakore i nga huarahi whakawhiti tohu tohu e pa ana ki te FGFR me te whakakore i te tipu o te pukupuku pukupuku me te mate pukupuku pukupuku i roto i te FGFR-overexpressing pūtau pukupuku. Ko te FGFR, he mea whakarite i roto i te maha o nga momo pūtau puku, he kaikawe tyrosine kinase e tika ana mo te tipu o te pūtau puku, te rereketanga me te oranga. |
| CPD3618 | TAS-120 | Ko te TAS-120 he aukati koiora-a-waha o te kaikawe fibroblast growth factor (FGFR) me te mahi antineoplastic pea. Ko te kaiwawao FGFR TAS-120 ka herea me te kore e taea te here me te aukati i te FGFR, ka puta pea te aukati i te ara whakawhiti tohu tohu-whakawaenga a FGFR me te tipu o te pūtau puku, me te nui ake o te mate o te pūtau i roto i nga pūtau pukupuku FGFR-overexpressing. Ko te FGFR he kaikawe tyrosine kinase e tika ana mo te tipu o te pūtau puku, te rereketanga me te oranga, me te whakataurite i ona korero i roto i te maha o nga momo pūtau puku. |
| CPDB1093 | Derazantinib; ARQ-087 | Ko Derazantinib, e mohiotia ana ko ARQ-087, he aukati koiora-a-waha o te kaikawe fibroblast growth factor (FGFR) me te mahi antineoplastic pea. |
| CPDB0942 | BLU-554 | Ko te BLU-554 he kaitautoko fibroblast growth factor receptor 4 (FGFR4) ka taea mo te maimoatanga o te mate pukupuku hepatocellular me te cholangiocarcinoma. |
| CPD0999 | H3B-6527 | Ko te H3B-6527 (H3 Biomedicine) he aukati FGFR4 tino whiriwhiri me te kaha o te mahi antitumour i roto i te FGF19 kua whakanuia nga raina pūtau me nga kiore. |
| CPD0997 | FGF401 | Ko te FGF-401 he aukati o te FGFR4 i tangohia mai i te patent WO2015059668A1, tauira pūhui 83; he IC50 o 1.9 nM. |
| CPDB0053 | AZD4547 | Ko te AZD 4547 he aukati whiriwhiri o te fibroblast growth factor receptor (FGFR) tyrosine kinase me nga uara IC50 o 0.2, 2.5, me te 1.8 nM mo te FGFR1, 2, me te 3, ia. |
| CPD3610 | BLU-9931 | Ko te BLU9931 te kaha, te whiriwhiri, me te kore e taea te whakakore i te aukati FGFR4 me te IC50 o 3 nM, mo te 297-, 184-, me te 50-fold selectivity i runga i te FGFR1 / 2/3, ia. |
