PI3K

CAT # Ingoa Hua Whakaahuatanga
CPD1573 GDC-0077 Ko te GDC-0077 he aukati PI3K e waatea ana me te mahi antineoplastic pea.
CPD1022 IPI-549 Ko te IPI549 he Inhibitor PI3Kγ kaha me te whiriwhiri me te IC50 o 16 nM.
CPDD3857 GDC-0326 Ko te GDC-0326 he kaitautoko kaha me te whiriwhiri i te α-Isoform o Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). Ko te GDC-0326 ka eke ki te taumata teitei o te whiriwhiringa i runga i etahi atu kinase. Ko te GDC-0326 he iti te plasma CL i roto i te tangata.
CPDB0202 AZD8186 Ko te AZD8186 me te aukati o te beta isoform o te phosphoinositide-3 kinase (PI3K), me te mahi antineoplastic pea.
CPDB1536 PQR530 Ko te PQR530 he tino kaha rua pan-PI3K / mTORC1 / 2 aukati.
CPDB1573 GDC-0077 Ko te GDC-0077 he aukati PI3K e waatea ana ma te waha me te whiriwhiri (IC50 = 0.038 + 0.003 nM) me te > 300-fold te whiriwhiri i runga i etahi atu momo tauira PI3K Class I.
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