AMG-510
Taipitopito Hua
Tohu Hua
| Rahi o te kete | Te waatea | Utu (USD) |
| 1g | kei roto i nga taonga | 1300 |
| 5g | kei roto i nga taonga | 6000 |
| 10g | kei roto i nga taonga | 10500 |
Ingoa matū:
4-((S)-4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl )pyrido[2,3-d]pyrimidin-2(1H)-one
Waehere SMILES:
O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C (C5=C(O)C=CC=C5F)=N4)=O)CC1
Waehere InChi:
InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8- 7-9-22(24)39)34-29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6- 11,14,16,18,39H,1,12-13,15H2,2-5H3/t18-/m0/s1
Kī InChi:
NXQKSXLFSAEQCZ-SFHVURJKSA-N
Kupumatua:
AMG-510; AMG 510; AMG510
Wairewa:
Rokiroki:
Whakaahuatanga:
Ko te AMG-510 he kaha kaha KRAS G12C aukati. Ko te AMG-510 e whai ana i te KRAS p.G12C mutant, i te DNA, RNA, i te taumata pūmua ranei, me te aukati, na roto i te ahua kaore ano kia whakamaramatia, te whakaputanga o te tohu me te / ranei te tohu pūtau puku ma te KRAS p.G12C mutant. Ma tenei ka aukati i te tipu o te KRAS p.G12C-whakaputa i nga pūtau puku
Whāinga: KRAS
