Alvocidib
Product Detail
Product Tags
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Nomen chemicum:
2-(2-chlorophenyl) -5,7-dihydroxy-8-((3R,4S)-3-hydroxy-1-methylpiperidin-4-yl) -4H-chromenlum-4-unum
SMILES Code:
O=C1C=C(C2=CC=CC=C2Cl)OC3=C([C@H]4[C@@H](O)CN(C)CC4)C(O)=CC(O)=C13
InChi Code:
InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21 19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17 +/m1/s1
InChi Key:
BIIVYFLTOXDAOV-PXAZEXFGSA-N
Keyword:
L 86-8275; L-868275; L 868275; L868275; HMR 1274; HMR-1274; HMR1274; Flavoperidol; Alvocidib
Solubilitas:
Repono:
Descriptio:
Alvocidib synthetica N-methylpiperidinyl chlorophenyl flavone compositum est. Sicut inhibitor cyclini-dependens kinasis, alvocidib cycli cellulae comprehensionem inducit impediendo phosphorylationem cyclini-dependens kinases (CDKs) et cyclinum D1 et D3 descensum expressio, inde in G1 cycli cellulae comprehensio et apoptosis. Hoc agens est etiam competitive inhibitor actionis adenosinae triphosphatae. Compesce pro iudiciis clinicis activis vel iudiciis clinicis clausis hoc agente utens.
Target: CDK
