Derazantinib; ARQ-087
Product Detail
Product Tags
| Pack Size | Availability | Pretium (USD) |
| 10mg | In Stock | 800 |
| 100mg | In Stock | 1200 |
| 500mg | In Stock | 1800 |
| Plus Sizes | Get Quotes | Get Quotes |
Nomen chemicum:
(6R)-6-(2-fluorophenyl)-5,6-dihydro-N-[3-[2-[(2-methoxyethyl)amino]ethyl]phenyl]-Benzo[h]quinazolin-2-amine
SMILES Code:
COCCNCCC1=CC(NC2=NC=C3C[C@@H](C4=CC=CC=C4F)C5=CC=CC=C5C3=N2)=CC=C1
InChi Code:
InChI=1S/C29H29FN4O/c1-35-16-15-31-14-13-20-7-6-8-22(17-20)33-29-32-19-21-18-26(24- 10-4-5-12-27(24)30)23-9-2-3-11-25(23)28(21)34-29/h2-12,17,19,26,31H,13- 16,18H2,1H3,(H,32,33,34)/t26-/m1/s1
InChi Key:
KPJDVVCDVBFRMU-AREMUKBSSA-N
Keyword:
ARQ-087, ARQ087, ARQ 087, 1234356-69-4
Solubilitas:Solutum in DMSO
Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).
Descriptio:
Derazantinib, etiam ARQ-087 notus, ore bioavailable inhibitor factoris fibroblast aucti receptoris (FGFR) cum actione antineoplastica potentiale. FGFR inhibitor ARQ 087 constringit et potenter vetat actionem subtyporum FGFR subtyporum 1, 2 et 3. Hoc evenire potest in inhibitione traductionis meatus FGFR mediatae, tumoris cellulae prolificationis, tumoris angiogenesis et tumoris cellae mortis in FGFR cellulis tumoris expressis. . FGFR, receptor kinasis tyrosinae, in multis tumoribus cellularum speciebus oriatur et in tumore cellularum multiplicatione, differentiatione, angiogenesi et superstite praecipuo munere funguntur.
Target: FGFR
