EED226
Product Detail
Product Tags
| Pack Size | Availability | Pretium (USD) |
| 25mg | In Stock | 300 |
| 50mg | In Stock | 500 |
| 100mg | In Stock | 800 |
Nomen chemicum:
N-(furan-2-ylmethyl)-8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine
SMILES Code:
O=S(C1=CC=C(C2=CN=C(NCC3=CC=CO3)N4C2=NN=C4)C=C1)(C)=O
InChi Code:
InChI=1S/C17H15N5O3S/c1-26(23,24)14-6-4-12(5-7-14)15-10-19-17(22-11-20-21-16(15)22) 18-9-13-3-2-8-25-13/h2-8,10-11H,9H2,1H3,(H,18,19)
InChi Key:
DYIRSNMPIZZNBK-UHFFFAOYSA-N
Keyword:
EED226, EED-226, EED 226, 2083627-02-3
Solubilitas:Solutum in DMSO
Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).
Descriptio:
EED226 inhibitor validissimus, efficax et selectivus est EZH2 et EZH1 contra latum amplitudinem scutorum epigeneticorum et non epigeneticorum aestimatarum. Signum in cellulis globalem H3K27Me3 potenter reducit et selective cellulas effectus necandi in cellulis Y641N mutationem heterozygoam gerentem demonstrat. EED226 moderatam habet permeabilitatem ut mensuratum in cellulis Caco-2 sub A →B=3.0x10-6 cm/s, effluxu ratione ad 7.6[1].
Target: EED226
