RGX-104 HCl
Product Detail
Product Tags
| Pack Size | Availability | Pretium (USD) |
| 100mg | In Stock | 500 |
| 500mg | In Stock | 800 |
| 1g | In Stock | 1200 |
| Plus Sizes | Get Quotes | Get Quotes |
Nomen chemicum:
(R)-2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]3-methylpropoxy]phenyl]acidi acetici hydrochloridi
SMILES Code:
O=C(O)CC1=CC=CC(OCC[C@H](N(CC2=CC=CC(C(F)(F)F)=C2Cl)CC(C3=CC=CC=C3)C4 =CC=CC=C4)C)=C1.[H]Cl
InChi Code:
InChI=1S/C34H33ClF3NO3.ClH/c1-24(18-19-42-29-168-10-25(20-29)21-32(40)41)39(22-28-15-9- 17-31(33(28)35)34(36,37)38)23-30(26-11-4-2-5-12-26)27-13-6-3-7-14-27; /h2-17,20,24,30H,18-19,21-23H2,1H3,(H,40,41);
InChi Key:
LCMIYQOJZLRHTO-GJFSDDNBSA-N
Keyword:
RGX-104 HCl, RGX-104, RGX104, RGX 104, 610318-03-1
Solubilitas:Solutum in DMSO
Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).
Descriptio:
RGX-104 est iecoris X receptor beta agonista cum potentiis actionibus immunodulantibus et antineoplasticis. In administratione orali, RGX-104 scuta selecta et ad LXRbeta ligat, inde LXRbeta-mediatum significans activum, ducens ad transcriptionem tumoris cuiusdam suppressoris genesis et downregulationis cuiusdam fautoris tumoris genesis. Hoc praecipue exprimit apolipoprotein E (ApoE), interdum suppressoris tumoris, in cellulis tumore et cellulis quibusdam immunibus. Haec ratio immunis innata operatur, inde per deperditionem cellularum suppressoris immunosuppressivorum myeloidarum (MDSCs), cellularum tumoris et cellularum endothelialium in tumore microenvironmentorum. Haec adversa evasio immunis, responsa immunes anti-tumorem auget et multiplicationem cellularum tumoris inhibet.
Target: LXRbeta
