GSK2982772

GSK2982772
  • Nomen:GSK2982772
  • Catalogue No.CPDD1123
  • CAS No.:1622848-92-3
  • Pondus hypotheticum:377.404
  • Formulae chemica:C20H19N5O3
  • Investigationes scientificae tantum, non aegros.

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    Nomen chemicum:

    (S) -5-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b]-[1,4]oxazepin-3-yl)-4H-1,2; 4-triazole-3-carboxamide

    SMILES Code:

    O=C(C1=NN=C(CC2=CC=CC=C2)N1)N[C@@H]3C(N(C)C4=CC=CC=C4OC3)=O

    InChi Code:

    InChI=1S/C20H19N5O3/c1-25-15-9-5-6-10-16(15)28-12-14(20(25)27)21-19(26)18-22-17(23- 24-18)11-13-7-3-2-4-8-13/h2-10,14H,11-12H2,1H3,(H,21,26)(H,22,23,24)/t14 -/m0/s1

    InChi Key:

    LYPAFUINURXJSG-AWEZNQCLSA-N

    Keyword:

    GSK-2982772, GSK 2982772, GSK2982772, 1622848-92-3

    Solubilitas:Solutum in DMSO

    Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).

    Descriptio:

    GSK2982772 receptor potens et selectivus Interacting Protein 1 (RIP1) Kinase Specific Fusce Candidatus ad tractationem morborum inflammationis. GSK2982772 est, nunc in periodo 2a studiorum clinicorum ad psoriasis, arthritis rheumatoideis, et colitis ulcerativis. GSK2982772 potenter se RIP1 cum exquisita kinasa specificitate obligat et in multis TNF responsabilibus cellulis dependens impedientibus optimam habet actionem. RIP1 emersit kinase magni momenti quae inflammatio moderari monstratum est per functiones specificas tam pegmata quam kinasa.

    Target: RIP1


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