H3B-6527

H3B-6527
  • Nomen:H3B-6527
  • Catalogue No.CPD0999
  • CAS No.:1702259-66-2
  • Pondus hypotheticum:629.54
  • Formulae chemica:C29H34Cl2N8O4
  • Investigationes scientificae tantum, non aegros.

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    Nomen chemicum:

    N-(2-((6-(3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-yl) phenyl) acrylamide

    SMILES Code:

    C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C)C(OC)=CC(OC)=C4Cl)=O)C) =C3)=O

    InChi Code:

    InChI=1S/C29H34Cl2N8O4/c1-6-25(40)35-20-14-18(39-12-10-38(7-2)11-13-39)8-9-19(20)34- 23-16-24(33-17-32-23)37(3 )29(41)36-28-26(30)21(42-4)15-22(43-5)27(28)31/h6,8-9,14-17H,1,7,10-13H2 4,2-5H3,(H,35,40)(H,36,41)(H,32,33,34)

    InChi Key:

    MBWRLLRCTIYXDW-UHFFFAOYSA-N

    Keyword:

    H3B-6527, H3B 6527, H3B6527, 1702259-66-2

    Solubilitas:Solutum in DMSO

    Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).

    Descriptio:

    H3B-6527 (H3 Biomedicina) est valde selectivum FGFR4 inhibitoris cum potenti antitumoure in FGF19 lineis cellulis et muribus ampliatis.

    Target: FGFR4




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