T-26c

Igama Lekhemikhali:

4-(((2-(3-methoxybenzyl)carbamoyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl)methoxy)methyl)benzoic acid

Ikhodi ye-SMILES:

O=C(O)C1=CC=C(COCC2=CSC(N=C(C(NCC3=CC=CC(OC)=C3)=O)N4)=C2C4=O)C=C1

Ikhodi ye-InChi:

I-InChI=1S/C24H21N3O6S/c1-32-18-4-2-3-15(9-18)10-25-22(29)20-26-21(28)19-17(13-34-23( 19)27- 20)12-33-11-14-5-7-16(8-6-14)24(30)31/h2-9,13H,10-12H2,1H3,(H,25,29)(H, 30,31)(H,26,27,28)

I-InChi Key:

CDQRIIUMNLMHRH-UHFFFAOYSA-N

Igama elingukhiye:

T-26c, T26c, T 26c, 869296-13-9

Ukunyibilika:I-Soluble ku-DMSO

Isitoreji:0 - 4°C isikhathi esifushane (izinsuku ukuya emavikini), noma -20°C isikhathi eside (izinyanga).

Incazelo:

I-T-26c iyisivimbeli se-metalloproteinases 13 (MMP-13) esinamandla kakhulu, esikhethayo futhi esivumela iseli. I-T-26c iphinde ivimbele ukuwohloka kwe-collagen ku-IL-1b kanye ne-oncostatin M evuselela uqwanga.

Ithagethi: MMP-13