I-AZD-7594
Imininingwane Yomkhiqizo
Omaka bomkhiqizo
| Usayizi Wephakethe | Ukutholakala | Intengo (USD) |
| 100mg | Kukhona kusitoki | 500 |
| 500mg | Kukhona kusitoki | 800 |
| 1g | Kukhona kusitoki | 1200 |
| Osayizi abengeziwe | Thola Izingcaphuno | Thola Izingcaphuno |
Igama Lekhemikhali:
3-(5-((1R,2S)-2-(2,2-difluoropropanamido)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl) propoxy)-1H-indazol -1-yl)-N-(tetrahydrofuran-3-yl)benzamide
Ikhodi ye-SMILES:
O=C(NC1COCC1)C2=CC=CC(N3N=CC4=C3C=CC(O[C@H](C5=CC=C(OCCO6)C6=C5)[C@@H](NC(C( F)(F)C)=O)C)=C4)=C2
Ikhodi ye-InChi:
I-InChI=1S/C32H32F2N4O6/c1-19(36-31(40)32(2,33)34)29(20-6-9-2 7-28(16-20)43-13-12-42-27)44-25-7-8-26-22(15-25)17-35-38(26) 24-5-3-4-21(14-24)30(39)37-23-10-11-41-18-23/h3-9,14-17,19,2 3,29H,10-13,18H2,1-2H3,(H,36,40)(H,37,39)/t19-,23?,29-/m0/s1
I-InChi Key:
ZZWJKLGCDHYVMB-QMQODZDESA-N
Igama elingukhiye:
AZD-7594, AZD 7594, AZD7594, AZ13189620, AZ-13189620, AZ 13189620, 1196509-60-0
Ukunyibilika:I-Soluble ku-DMSO
Isitoreji:0 - 4°C isikhathi esifushane (izinsuku ukuya emavikini), noma -20°C isikhathi eside (izinyanga).
Incazelo:
I-AZD-7594, eyaziwa nangokuthi i-AZ13189620, iyimoduli ekhethiwe ye-glucocorticoid receptor (GCCR). I-AZD-7594 isesigabeni sesi-II sokuhlolwa komtholampilo yi-AstraZeneca ukuze zelashwe isifuba somoya esithambile esimaphakathi. Kusesigabeni soku-I sokuhlolwa kwemitholampilo yokwelashwa kwe-chronic obstructive pulmonary disorder (COPD).
Ithagethi: GCCR
