I-Ozanimod

I-Ozanimod
  • Igama:Ozanimod, RPC1063
  • Inombolo yekhathalogi:I-CPD3744
  • Inombolo ye-CAS:1306760-87-1
  • Isisindo se-Molecular:404.46
  • I-Chemical Formula:I-C23H24N4O3
  • Olocwaningo lwesayensi kuphela, hhayi lweziguli.

    Imininingwane Yomkhiqizo

    Omaka bomkhiqizo

    Usayizi Wephakethe Ukutholakala Intengo (USD)
    1g Kukhona kusitoki 200
    5g Kukhona kusitoki 800
    10g Kukhona kusitoki 1200
    Osayizi abengeziwe Thola Izingcaphuno Thola Izingcaphuno

    Igama Lekhemikhali:

    (S)-5-(3-(1-((2-hydroxyethyl)amino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2 - isopropoxybenzonitrile

    Ikhodi ye-SMILES:

    N#CC1=CC(C2=NC(C3=CC=CC4=C3CC[C@@H]4NCCO)=NO2)=CC=C1OC(C)C

    Ikhodi ye-InChi:

    I-InChI=1S/C23H24N4O3/c1-14(2)29-21-9-6-15(12-16(21)13-24)23-26-22(27-30-23)19-5-3- 4-18-17(19)7-8-20(18)25-10-11-28/h3-6,9,12,14,20,25,28H,7-8,10-11H2,1- 2H3/t20-/m0/s1

    I-InChi Key:

    XRVDGNKRPOAQTN-FQEVSTJZSA-N

    Igama elingukhiye:

    Ozanimod, RPC-1063, RPC1063, RPC 1063, 1306760-87-1

    Ukunyibilika:I-Soluble ku-DMSO

    Isitoreji:0 - 4°C isikhathi esifushane (izinsuku ukuya emavikini), noma -20°C isikhathi eside (izinyanga).

    Incazelo:

    I-Ozanimod iyimoduli ekhethiwe, etholakala ngomlomo ye-sphingosine-1-phosphate (S1P) receptors S1P1 kanye ne-SIP5. Idala ukufakwa ngaphakathi kwe-S1P1, inciphisa ukujikeleza kwama-lymphocyte e-B kanye ne-CCR7(+) T, futhi inciphisa ukuvuvukala nemingcele yezifo kumamodeli amathathu esifo sokuzivikela komzimba.1 I-Ozanimod isezivivinyweni zomtholampilo zokubuyela emuva kwe-multiple sclerosis kanye ne-ulcerative colitis.

    Ithagethi: S1P


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