I-Ozanimod
Imininingwane Yomkhiqizo
Omaka bomkhiqizo
Usayizi Wephakethe | Ukutholakala | Intengo (USD) |
1g | Kukhona kusitoki | 200 |
5g | Kukhona kusitoki | 800 |
10g | Kukhona kusitoki | 1200 |
Osayizi abengeziwe | Thola Izingcaphuno | Thola Izingcaphuno |
Igama Lekhemikhali:
(S)-5-(3-(1-((2-hydroxyethyl)amino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2 - isopropoxybenzonitrile
Ikhodi ye-SMILES:
N#CC1=CC(C2=NC(C3=CC=CC4=C3CC[C@@H]4NCCO)=NO2)=CC=C1OC(C)C
Ikhodi ye-InChi:
I-InChI=1S/C23H24N4O3/c1-14(2)29-21-9-6-15(12-16(21)13-24)23-26-22(27-30-23)19-5-3- 4-18-17(19)7-8-20(18)25-10-11-28/h3-6,9,12,14,20,25,28H,7-8,10-11H2,1- 2H3/t20-/m0/s1
I-InChi Key:
XRVDGNKRPOAQTN-FQEVSTJZSA-N
Igama elingukhiye:
Ozanimod, RPC-1063, RPC1063, RPC 1063, 1306760-87-1
Ukunyibilika:I-Soluble ku-DMSO
Isitoreji:0 - 4°C isikhathi esifushane (izinsuku ukuya emavikini), noma -20°C isikhathi eside (izinyanga).
Incazelo:
I-Ozanimod iyimoduli ekhethiwe, etholakala ngomlomo ye-sphingosine-1-phosphate (S1P) receptors S1P1 kanye ne-SIP5. Idala ukufakwa ngaphakathi kwe-S1P1, inciphisa ukujikeleza kwama-lymphocyte e-B kanye ne-CCR7(+) T, futhi inciphisa ukuvuvukala nemingcele yezifo kumamodeli amathathu esifo sokuzivikela komzimba.1 I-Ozanimod isezivivinyweni zomtholampilo zokubuyela emuva kwe-multiple sclerosis kanye ne-ulcerative colitis.
Ithagethi: S1P