I-SYK

IKATI #	Igama Lomkhiqizo	Incazelo
I-CPDD3529	I-PRT-060318; I-PRT318; P142–76	I-PRT060318 iyi-inhibitor enamandla futhi ekhethayo ye-spleen tyrosine kinase (Syk; IC50 = 4 nM). Iyakhetha, ivimbela u-92% womsebenzi we-Syk, kuyilapho amanye ama-kinase egcina umsebenzi ongu->70%, ekuhlanganiseni okungu-50 nM kuphaneli ye-Syk. 270 ama-kinases.
I-CPDD1851	I-BAY 61-3606 2HCl	I-BAY 61-3606 inamandla (Ki = 7.5 nM) kanye ne-inhibitor ekhethiwe ye-Syk kinase.