in vitro Pharmacokinetic Assays

Ithimba lethu le-pharmacokinetic ligxile ekuthuthukisweni kwangaphambi komtholampilo, ukuhlolwa kwe-DMPK nokubhaliswa kwe-IND. Sakhe inkundla edidiyelwe ye-in vitro & in vivo yokuhlola ubuchwepheshe ukuze sisekele ukutholwa nokuthuthukiswa kwezidakamizwa. I-Caerulum Pharma inikeza isevisi evumelana nezimo neyomuntu siqu ukuze uthole izixazululo ze-DMPK ezisebenza kahle nezingabizi ukuze uqhubekisele phambili ucwaningo lwakho.

1.Izingxenye zokufunda

Ama-molecule amancane, imikhiqizo yemvelo, ama-polypeptides.

2.Amasevisi atholakalayo

Ukuhlolwa kokubopha amaprotheni e-Plasma/tissue

Isilinganiso se-plasma negazi

Ukuqina kwe-metabolism ye-microsomal yesibindi

Ukuzinza emotweni nakuplasma

Ukuhlonza i-Metabolite

I-CYP yokusabela phenotyping

Ukuvinjelwa kwe-CYP

3.Ekwakhiweni

I-Hepatocyte Induction

I-Caco-2 Permeability

Ukusabela kwe-UGT phenotyping


...
Ingxoxo ye-WhatsApp Online!