I-PI3K

IKATI # Igama Lomkhiqizo Incazelo
I-CPD1573 I-GDC-0077 I-GDC-0077 iyi-PI3K inhibitor etholakala ngomlomo ekwazi ukwenza umsebenzi we-antineoplastic.
I-CPD1022 IPI-549 I-IPI549 iyi-PI3Kγ Inhibitor enamandla futhi ekhethayo ene-IC50 ye-16 nM.
I-CPDD3857 I-GDC-0326 I-GDC-0326 iyi-inhibitor enamandla futhi ekhethayo ye-α-Isoform ye-Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). I-GDC-0326 ifinyelela izinga eliphezulu kakhulu lokukhetha ngaphezu kwamanye ama-kinases. I-GDC-0326 ine-plasma CL ephansi kumuntu.
I-CPDB0202 I-AZD8186 I-AZD8186 iyisivimbeli se-beta isoform ye-phosphoinositide-3 kinase (PI3K), enekhono lomsebenzi we-antineoplastic.
Idatha ye-CPDB1536 I-PQR530 I-PQR530 iyi-dual inhibitor ekabili ye-pan-PI3K/mTORC1/2 enamandla kakhulu.
Idatha ye-CPDB1573 I-GDC-0077 I-GDC-0077 iyi-PI3K inhibitor etholakala ngomlomo futhi ekhethiwe (IC50 = 0.038 + 0.003 nM) ene > ekhethwa ngokuphindwe ka-300 ngaphezu kwamanye ama-isoform e-Class I PI3K.
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