IKATI # | Igama Lomkhiqizo | Incazelo |
I-CPD1573 | I-GDC-0077 | I-GDC-0077 iyi-PI3K inhibitor etholakala ngomlomo ekwazi ukwenza umsebenzi we-antineoplastic. |
I-CPD1022 | IPI-549 | I-IPI549 iyi-PI3Kγ Inhibitor enamandla futhi ekhethayo ene-IC50 ye-16 nM. |
I-CPDD3857 | I-GDC-0326 | I-GDC-0326 iyi-inhibitor enamandla futhi ekhethayo ye-α-Isoform ye-Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). I-GDC-0326 ifinyelela izinga eliphezulu kakhulu lokukhetha ngaphezu kwamanye ama-kinases. I-GDC-0326 ine-plasma CL ephansi kumuntu. |
I-CPDB0202 | I-AZD8186 | I-AZD8186 iyisivimbeli se-beta isoform ye-phosphoinositide-3 kinase (PI3K), enekhono lomsebenzi we-antineoplastic. |
Idatha ye-CPDB1536 | I-PQR530 | I-PQR530 iyi-dual inhibitor ekabili ye-pan-PI3K/mTORC1/2 enamandla kakhulu. |
Idatha ye-CPDB1573 | I-GDC-0077 | I-GDC-0077 iyi-PI3K inhibitor etholakala ngomlomo futhi ekhethiwe (IC50 = 0.038 + 0.003 nM) ene > ekhethwa ngokuphindwe ka-300 ngaphezu kwamanye ama-isoform e-Class I PI3K. |