IKATI # | Igama Lomkhiqizo | Incazelo |
CPDB1974 | I-GSK-461364 | I-GSK461364 ngokuncika kumthamo imisa ukuhamba kwamabhayisikili emigqeni yamaseli omdlavuza andayo ahlukahlukene futhi, ngemithamo ephezulu, icuphe i-apoptosis. Kubonakala kusebenza kakhulu ngokumelene namathumba angenayo i-p53 futhi iyakwazi ukweqa umgoqo wegazi nobuchopho. I-GSK461364 iyasebenza ku-vivo, idala ukuvimbela ukukhula kwesimila noma ukubambezeleka kokukhula kumamodeli we-xenograft kumagundane. |