| CAT # | Mahsulot nomi | Tavsif |
| CPDB1974 | GSK-461364 | GSK461364 dozaga bog'liq ravishda turli xil proliferatsiyalanuvchi saraton hujayralari qatorlarida hujayra aylanishini to'xtatadi va yuqori dozalarda apoptozni qo'zg'atadi. Ko'rinib turibdiki, u p53 etishmovchiligi bo'lgan o'smalarga qarshi samaraliroq va qon-miya to'sig'ini kesib o'tishga qodir. GSK461364 in vivo samarali bo'lib, sichqonlarda ksenograft modellarida o'simta o'sishini inhibe qilish yoki o'sish kechikishini keltirib chiqaradi. |
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