AMG-510
Mahsulot detali
Mahsulot teglari
| Paket hajmi | Mavjudligi | Narxi (AQSh dollari) |
| 1g | omborda mavjud; sotuvda mavjud | 1300 |
| 5g | omborda mavjud; sotuvda mavjud | 6000 |
| 10 g | omborda mavjud; sotuvda mavjud | 10500 |
Kimyoviy nomi:
4-((S)-4-akriloil-2-metilpiperazin-1-il)-6-ftor-7-(2-ftor-6-gidroksifenil)-1-(2-izopropil-4-metilpiridin-3-il) )pirido[2,3-d]pirimidin-2(1H)-bir
SMILE kodi:
O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C (C5=C(O)C=CC=C5F)=N4)=O)CC1
InChi kodi:
InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8- 7-9-22(24)39)34-29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6- 11,14,16,18,39H,1,12-13,15H2,2-5H3/t18-/m0/s1
InChi kaliti:
NXQKSXLFSAEQCZ-SFHVURJKSA-N
Kalit so'z:
AMG-510; AMG 510; AMG510
Eruvchanligi:
Saqlash:
Tavsif:
AMG-510 kuchli KRAS G12C kovalent inhibitori. AMG-510 DNK, RNK yoki oqsil darajasida KRAS p.G12C mutantini tanlab nishonga oladi va hali aniqlanmagan tarzda KRAS p.G12C mutant orqali o'simta hujayralarining ifodalanishi va/yoki signalizatsiyasini oldini oladi. Bu KRAS p.G12C ifodalovchi o'simta hujayralarining o'sishiga to'sqinlik qilishi mumkin
Maqsad: KRAS
