Luxdegalutamide; ARV-766
Rincian produk
Tag produk
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Ngaran Kimia:
4-(4-((1-(4-(((1r,3r))-3-(4-cyano-3-methoxyphenoxy)) -2,2,4,4-tetramethylcyclobutyl)carbamoyl)fenil)piperidin-4- yl)metil)piperazin-1-yl)-N-((S)-2,6-dioxopiperidin-3-yl)-2-fluorobenzamide
Kode SMILES:
CC1(C)[C@H](NC(C2=CC=C(N3CCC(CN4CCN(C5=CC(F))=C(C(N[C@@H])6C(=O)NC(=O)) CC6)=O)C=C5)CC4)CC3)C=C2)=O)C(C)(C)[C@H]1OC1=CC(OC)=C(C#N)C=C1
Kodeu InChi:
InChI=1S/C45H54FN7O6/c1-44(2)42(45(3,4)43(44)59-33-12-8-30(26-47)37(25-33)5 8-5)50-39(55)29-6-9-31(10-7-29)52-18-16-28(17-19-52)27-51-20-22-53(23- 21-51) 32-11-13-34(35(46)24-32)40(56)48-36-14-15-38(54)49-41(36)57/h6-13,24-25,28, 36,42-43H,14-23,27H2,1-5H3,(H,48,56)(H,50,55)(H,49,54,57)/t36-,42-,43-/m0 /s1
Konci InChi:
RDPPBRKNBBXPNZ-FMPIRMQTSA-N
kecap konci:
2750830-09-0；CAS:2750830-09-0；CAS:2750830-09-0；ARV766; ARV 766; ARV-766; GTPL12624; luxdegalutamide
Kalarutan:
Panyimpenan:Garing, poék sareng dina 0 - 4 C kanggo jangka pondok (poé ka minggu) atanapi -20 C kanggo jangka panjang (bulan ka taun).
Katerangan:
Luxdegalutamide (ARV-766) mangrupikeun hidrolisis protéin sasaran chimeric (PROTAC) anu épéktip sacara lisan anu nargétkeun reséptor androgén (AR), anu tiasa nguraikeun mutan résistansi AR.
Sasaran: AR
